منابع مشابه
Ribosomes and protein synthesis
Let us start at the very beginning. Between 1897 and 1899, G. Gamier, in France, published elegant microscope studies describing a basophilic component ofthe cytoplasm of glandular cells (1) . Because of what he thought its role might be in the elaboration and transformation of secretory products, he gave a Greek name to these concepts-ergastoplasm (work plasm) . Gamier's research was extended ...
متن کاملProtein synthesis by single ribosomes.
The ribosome is universally responsible for synthesizing proteins by translating the genetic code transcribed in mRNA into an amino acid sequence. Ribosomes use cellular accessory proteins, soluble transfer RNAs, and metabolic energy to accomplish the initiation, elongation, and termination of peptide synthesis. In translocating processively along the mRNA template during the elongation cycle, ...
متن کاملMessenger RNA and ribosomes in protein synthesis.
The Biochemical Society's Forty-Seventh Symposium, held in London in December 1981, assembled some of the leading workers in this area of biochemistry. The subjects for discussion were chosen for their timeliness and distinctiveness, and included accounts of ribosome and messenger RNA structure and function, initiation factors, caps and ribonucleoproteins, as well as consideration of the proces...
متن کاملSynthesis of protein, ribonucleic acid, and ribosomes by individual bacterial cells in balanced growth.
Relative rates of protein synthesis in individual cells were determined by allowing random populations to incorporate tritiated leucine for very short periods (pulses) and then examining autoradiographs of these cells to assess the amount of incorporation (grains per cell) as a function of cell size. Relative rates of ribonucleic acid (RNA) synthesis were determined in the same way by using tri...
متن کاملConformational changes in ribosomes during protein synthesis.
In a purified system containing poly(U) and ribosomal subunits from Escherichia coli, and purified transfer factors T and G, the active ribosomal complex passes through a cycle of contraction and expansion with the addition of each amino acid; aminoacyl-tRNA binding catalyzed by T produces the stable compact state, corresponding to the 70S conformation, whereas translocation with G expands the ...
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ژورنال
عنوان ژورنال: Journal of General Microbiology
سال: 1962
ISSN: 0022-1287
DOI: 10.1099/00221287-29-1-53